Magma (New York, N.Y.) · 2026
Abdominal T1 relaxation times at 7T.
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Bulanov Petr, Menshchikov Petr, Grimm Johannes A, Himburg Niklas, Schmidt Simon, Orzada Stephan, Ladd Mark E, Schmitter Sebastian
Аннотация
OBJECTIVE: To quantify the T1 relaxation times at 7T for key abdominal organs and tissues, including the liver, kidney, spleen, and skeletal paraspinal muscles.
MATERIALS AND METHODS: T1 mapping was performed on a 7T whole-body scanner with a parallel transmission (pTx) system in five healthy volunteers. Static pTx (B1+ shimming) was applied to maximize B1+ magnitude in the target region. For each T1 map, data were collected using eight snapshot gradient-echo inversion recovery sequences during breath holding. Voxel-wise T1 values were calculated based on DICOM data using exponential model fitting.
RESULTS: Mean abdomen T1 values and corresponding coefficients of variation across the group were: 1829 ± 60 ms, 3.3% for the kidney cortex; 2619 ± 83 ms, 3.2% for the kidney medulla; 1378 ± 48 ms, 3.5% for the liver; 1954 ± 28 ms, 1.4% for the skeletal paraspinal muscle; 1770 ± 36 ms, 2.0% for the spleen.
CONCLUSION: In this study, we quantified the T1 relaxation times at 7T for key abdominal organs and tissues, including the liver, kidney, spleen, and skeletal paraspinal muscle. To achieve this, pTx was applied to mitigate B1+ dropouts in the target regions. The B1+ insensitive snapshot gradient-echo inversion recovery method was utilized to acquire accurate and reproducible T1 maps.
MATERIALS AND METHODS: T1 mapping was performed on a 7T whole-body scanner with a parallel transmission (pTx) system in five healthy volunteers. Static pTx (B1+ shimming) was applied to maximize B1+ magnitude in the target region. For each T1 map, data were collected using eight snapshot gradient-echo inversion recovery sequences during breath holding. Voxel-wise T1 values were calculated based on DICOM data using exponential model fitting.
RESULTS: Mean abdomen T1 values and corresponding coefficients of variation across the group were: 1829 ± 60 ms, 3.3% for the kidney cortex; 2619 ± 83 ms, 3.2% for the kidney medulla; 1378 ± 48 ms, 3.5% for the liver; 1954 ± 28 ms, 1.4% for the skeletal paraspinal muscle; 1770 ± 36 ms, 2.0% for the spleen.
CONCLUSION: In this study, we quantified the T1 relaxation times at 7T for key abdominal organs and tissues, including the liver, kidney, spleen, and skeletal paraspinal muscle. To achieve this, pTx was applied to mitigate B1+ dropouts in the target regions. The B1+ insensitive snapshot gradient-echo inversion recovery method was utilized to acquire accurate and reproducible T1 maps.