Low-Level Light Therapy as a Potential Adjunctive Approach in Mucus Fishing Syndrome: Report of Two Clinical Cases.

Mucus Fishing Syndrome (MFS) is a chronic inflammatory condition of the ocular surface characterized by repeated mechanical removal of mucus strands, leading to a cycle of irritation and excess mucus production. MFS is often associated with dry eye disease, meibomian gland dysfunction, blepharitis, and allergic conjunctivitis. Patients typically present with conjunctival hyperemia, irritation, and mucus accumulation. We describe two clinical cases of MFS in which low-level light therapy (LLLT) was used as part of a multimodal management approach. The first case involved a 32-year-old woman with a 2-year history of persistent symptoms despite previous treatments. The second case was a 50-year-old woman with severe discomfort and chronic mucus secretion unresponsive to tear substitutes alone. Both patients underwent conservative therapy including topical corticosteroids, acetylcysteine 5%, eyelid hygiene, and adjunctive LLLT (4 sessions in case #1 and 5 in case #2). MFS remains a challenging ocular surface condition requiring combined management of inflammation, mucin hypersecretion, and behavioral factors. In the cases presented, LLLT was incorporated as an adjunctive intervention within a broader therapeutic plan. Although improvement was observed, the contribution of LLLT cannot be determined based on these findings alone and further studies are needed to clarify its potential role in MFS management.