Klinische Monatsblatter fur Augenheilkunde · 1994
[Arteriosclerosis of the orbital arteries].
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Dyrka B, Iselin S, Büchi E R
Аннотация
BACKGROUND: The anatomy of the orbital arteries is well known, and their physiology is under intensive investigation. Their age-related or other pathologic alterations, however, are still largely unknown.
METHOD: We obtained at autopsy 16 orbits from 8 persons aged > 70 years, and 4 orbits from 2 persons between 40 and 50 years. Specimens were taken from 20 locations along the orbital arteries, from the internal carotid to the globe, and studied by light microscopy.
RESULTS: We observed the following arteriosclerotic changes, in order of decreasing frequency: intimal hyperplasia, medial atrophy, atherosclerotic fibrous plaques, and calcifications of the internal elastic lamina. The frequency and severity generally decreased with smaller arterial caliber.
CONCLUSION: Arteriosclerosis was ubiquitous in persons > 70 years of age. Degenerative changes in aged human orbital arteries may play an important role in ophthalmic vascular diseases.
METHOD: We obtained at autopsy 16 orbits from 8 persons aged > 70 years, and 4 orbits from 2 persons between 40 and 50 years. Specimens were taken from 20 locations along the orbital arteries, from the internal carotid to the globe, and studied by light microscopy.
RESULTS: We observed the following arteriosclerotic changes, in order of decreasing frequency: intimal hyperplasia, medial atrophy, atherosclerotic fibrous plaques, and calcifications of the internal elastic lamina. The frequency and severity generally decreased with smaller arterial caliber.
CONCLUSION: Arteriosclerosis was ubiquitous in persons > 70 years of age. Degenerative changes in aged human orbital arteries may play an important role in ophthalmic vascular diseases.