Tropical medicine & international health : TM & IH · 2007
Evaluation of the diethylcarbamazine patch to evaluate onchocerciasis endemicity in Central Africa.
Оценочное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ozoh Gladys, Boussinesq Michel, Bissek Anne-Cécile Zoung-Kanyi, Kobangue Léon, Kombila Maryvonne, Mbina Jean-Romain Mourou, Enyong Peter, Noma Mounkaïla, Sékétéli Azodoga, Fobi Grace
Аннотация
OBJECTIVE: As part of a baseline data collection for assessing the impact of the African Programme for Onchocerciasis Control, to evaluate the diethylcarbamazine (DEC) patch test in determining the endemicity of onchocerciasis.
METHOD: A total of 226 untreated children aged 3-5, living in four selected endemic foci, in Cameroon, Gabon and Central African Republic, were tested. Observed graded skin reactions to the patch were analysed and compared with the prevalence of onchocercal nodules and reactive skin disease in the corresponding community.
RESULTS: The proportion of children who tested positive ranged from 25.0% to 77.1%. The values were closely correlated with the prevalence of nodules, i.e. the level of endemicity for onchocerciasis.
CONCLUSION: The DEC patch test, which has been so far used only in West African foci of onchocerciasis, can also constitute a valuable tool to evaluate the levels of endemicity of onchocerciasis in Central Africa, and to follow-up the intensity of transmission of Onchocerca volvulus.
METHOD: A total of 226 untreated children aged 3-5, living in four selected endemic foci, in Cameroon, Gabon and Central African Republic, were tested. Observed graded skin reactions to the patch were analysed and compared with the prevalence of onchocercal nodules and reactive skin disease in the corresponding community.
RESULTS: The proportion of children who tested positive ranged from 25.0% to 77.1%. The values were closely correlated with the prevalence of nodules, i.e. the level of endemicity for onchocerciasis.
CONCLUSION: The DEC patch test, which has been so far used only in West African foci of onchocerciasis, can also constitute a valuable tool to evaluate the levels of endemicity of onchocerciasis in Central Africa, and to follow-up the intensity of transmission of Onchocerca volvulus.