[A Case of Malignant Transformation of Previously Diagnosed Oral Leukoplakia].

Oral leukoplakia is the most common premalignant and potentially malignant lesion of the oral mucosa. Several studies have reported that the prevalence of oral cancer in young people is increasingly rapidly. The patient in this report was a 47- year-old man who complained of left tongue discomfort. At the first visit, the clinical diagnosis was oral leukoplakia, and a follow-up examination was planned with a view to partial resection. However, at the follow-up, biopsy revealed squamous cell carcinoma. He underwent partial resection. Two months after the surgery, metastasis to the lymph node was detected. The patient underwent radical neck dissection and concurrent chemoradiotherapy. At the 3-years follow-up, there was no sign of recurrence or metastasis.