Modern rheumatology · 2011
A patient with systemic lupus erythematosus who developed massive small intestinal hemorrhaging during treatment for chronic lupus peritonitis.
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Kawashiri Shin-ya, Nishino Ayako, Sueyoshi Eijun, Okada Akitomo, Koga Tomohiro, Yamasaki Satoshi, Nakamura Hideki, Origuchi Tomoki, Kawakami Atsushi
Аннотация
A 50-year-old Japanese woman, a patient with systemic lupus erythematosus (SLE) complicated with chronic lupus peritonitis, developed massive small intestinal hemorrhaging. She was treated with intravenous pulse of methylprednisolone, intravenous pulse of cyclophosphamide (IVCY), and immunoabsorption, but the peritonitis was refractory to these treatments. Subsequently, she was treated with oral corticosteroid and tacrolimus, and received IVCY monthly, but she developed massive small intestinal hemorrhaging 1 year after. Abdominal angiography detected multiple bleeding sites from the jejunal and ileal arteries. After transarterial embolization treatment, the melena disappeared. The pathology of this case appeared to be lupus mesenteric vasculitis.
Предметные рубрики MeSH
Combined Modality TherapyCyclophosphamideEmbolization, TherapeuticFemaleGastrointestinal HemorrhageHumansImmunosorbent TechniquesImmunosuppressive AgentsInjections, IntravenousIntestinal DiseasesIntestine, SmallLupus Erythematosus, SystemicMethylprednisoloneMiddle AgedPeritonitisPulse Therapy, DrugTreatment FailureTreatment OutcomeVasculitis