Deutsche medizinische Wochenschrift (1946) · 2000
[Mediastinal space-occupying lesion of uncertain histology: difficulties of differential diagnosis].
Клинический случайСравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Grundmann J, Wolff T
Аннотация
HISTORY AND ADMISSION FINDINGS: A 78-year-old woman had, for the previous 4 months, been aware of an easily moveable tumour in the jugular region. She had been feeling well except for general fatigue. Physical examination revealed a mass in the jugular region, a little over 2 cm in diameter.
INVESTIGATIONS: Routine laboratory tests were normal, except for a raised erythrocyte sedimentation rate. After ultrasound, scintigraphy and computed tomography, a biopsy was performed. Histologically it was suspicious of a centroblastic centrocytic non-Hodgkin lymphoma, but further pathological investigation established the diagnosis of a malignant thymoma.
TREATMENT AND COURSE: The tumour was resected and histological examination confirmed a malignant thymoma with infiltration of surrounding tissues. Radiotherapy was subsequently undertaken.
CONCLUSION: Even though its evidence is low, a malignant thymoma or benign thymic tumour should be included in the differential diagnosis of a space-occupying mediastinal mass of unclear histology.
INVESTIGATIONS: Routine laboratory tests were normal, except for a raised erythrocyte sedimentation rate. After ultrasound, scintigraphy and computed tomography, a biopsy was performed. Histologically it was suspicious of a centroblastic centrocytic non-Hodgkin lymphoma, but further pathological investigation established the diagnosis of a malignant thymoma.
TREATMENT AND COURSE: The tumour was resected and histological examination confirmed a malignant thymoma with infiltration of surrounding tissues. Radiotherapy was subsequently undertaken.
CONCLUSION: Even though its evidence is low, a malignant thymoma or benign thymic tumour should be included in the differential diagnosis of a space-occupying mediastinal mass of unclear histology.