The prognostic value of CA-125 in epithelial ovarian cancer patients during and after chemotherapy.

In the past ten years the investigations on CA-125 levels of epithelial ovarian cancer patients have raised several questions both in the screening and in the follow-up. The predictive value of the test during the postoperative chemotherapy and the follow-up period was the topic in the series of examinations. Our findings are as follows. The decrease of the CA-125 level predicts a long tumour free survival. The permanent high level of CA-125 is a signal of a recurrence within few month after stopping therapy. In case of increase of the CA-125 level an early recurrence can be expected.