Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2009
[Effect of nutritional support on immune function in patients with severe pulmonary infection after renal transplantation].
Аннотация на английскомСтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Cheng Xue-Tao, Li Sheng-Ling, Liu Guo-Lian, Yang Xiao-Ming, Lu Jun
Аннотация
OBJECTIVE: To study the effect of parenteral plus enteral nutrition (PN+EN) and total parenteral nutrition (TPN) support on the postoperative immune function in renal recipients with severe pulmonary infection.
METHODS: Twenty renal recipients with severe postoperative pulmonary infection were randomly assigned into two equal groups to receive PN+EN or standard TPN, both supplied with equal nitrogen and calorie. The plasma levels of total protein, albumin, hemoglobin and peripheral blood IgA, IgG, IgM, total lymphocyte count, and CD4/CD8 ratio were measured before and after the treatment.
RESULTS: The total lymphocyte count, CD4/CD8 ratio and IgG were significantly increased in patients receiving PN+EN as compared with those in TPN group (P<0.05). In both of the groups, the total protein and albumin levels underwent no significant changes after the nutritional support (P>0.05).
CONCLUSION: PN+EN can better improve the immune function than TPN in renal recipients with severe pulmonary infection.
METHODS: Twenty renal recipients with severe postoperative pulmonary infection were randomly assigned into two equal groups to receive PN+EN or standard TPN, both supplied with equal nitrogen and calorie. The plasma levels of total protein, albumin, hemoglobin and peripheral blood IgA, IgG, IgM, total lymphocyte count, and CD4/CD8 ratio were measured before and after the treatment.
RESULTS: The total lymphocyte count, CD4/CD8 ratio and IgG were significantly increased in patients receiving PN+EN as compared with those in TPN group (P<0.05). In both of the groups, the total protein and albumin levels underwent no significant changes after the nutritional support (P>0.05).
CONCLUSION: PN+EN can better improve the immune function than TPN in renal recipients with severe pulmonary infection.