[Effect of nutritional support on immune function in patients with severe pulmonary infection after renal transplantation].

OBJECTIVE

To study the effect of parenteral plus enteral nutrition (PN+EN) and total parenteral nutrition (TPN) support on the postoperative immune function in renal recipients with severe pulmonary infection.

METHODS

Twenty renal recipients with severe postoperative pulmonary infection were randomly assigned into two equal groups to receive PN+EN or standard TPN, both supplied with equal nitrogen and calorie. The plasma levels of total protein, albumin, hemoglobin and peripheral blood IgA, IgG, IgM, total lymphocyte count, and CD4/CD8 ratio were measured before and after the treatment.

RESULTS

The total lymphocyte count, CD4/CD8 ratio and IgG were significantly increased in patients receiving PN+EN as compared with those in TPN group (P<0.05). In both of the groups, the total protein and albumin levels underwent no significant changes after the nutritional support (P>0.05).

CONCLUSION

PN+EN can better improve the immune function than TPN in renal recipients with severe pulmonary infection.