American journal of contact dermatitis : official journal of the American Contact Dermatitis Society · 1997
Three cases of contact allergy after chemical burns from methylchloroisothiazolinone/methylisothiazolinone: one with concomitant allergy to methyldibromoglutaronitrile/phenoxyethanol.
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Primka E J, Taylor J S
Аннотация
BACKGROUND: Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is known to be a contact sensitizer. It is used extensively in cosmetic products in low concentrations. Occupational exposure usually occurs with concentrated solutions and results in a different reaction pattern.
RESULTS: Three workers developed chemical burns and subsequent sensitization after exposure to concentrated solutions of MCI/MI. One patient was also occupationally sensitized to methyldibromoglutaronitrile/phenoxyethanol.
CONCLUSION: Exposure to concentrated solutions of some allergens can be severely irritating in the occupational setting and can probably induce sensitization.
RESULTS: Three workers developed chemical burns and subsequent sensitization after exposure to concentrated solutions of MCI/MI. One patient was also occupationally sensitized to methyldibromoglutaronitrile/phenoxyethanol.
CONCLUSION: Exposure to concentrated solutions of some allergens can be severely irritating in the occupational setting and can probably induce sensitization.