Biomarkers in medicine · 2019
Predictive value of platelet-to-lymphocyte ratio in patients with sarcoidosis.
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Yalnız Enver, Karadeniz Gülistan, Üçsular Fatma Demirci, Erbay Polat Gülru, Şahin Görkem Vayısoğlu
Аннотация
AIM: We aimed to evaluate platelet-to-lymphocyte ratio (PLR) in patients with sarcoidosis.
METHODS: A total of 310 sarcoidosis patients and 220 healthy controls retrospectively were recorded in this study.
RESULTS: PLR was significantly higher in patients with sarcoidosis than in the control group, and was also significantly higher in patients with pulmonary involvement in stage 2-3-4 than in stage 1. PLR were significantly positive correlated with erythrocyte sedimentation rate. The cut-off values for PLR for predicting a sarcoidosis diagnosis were determined as 158.
CONCLUSION: Increase in PLR value can be used for guiding both the diagnosis of sarcoidosis and the involvement of parenchyma.
METHODS: A total of 310 sarcoidosis patients and 220 healthy controls retrospectively were recorded in this study.
RESULTS: PLR was significantly higher in patients with sarcoidosis than in the control group, and was also significantly higher in patients with pulmonary involvement in stage 2-3-4 than in stage 1. PLR were significantly positive correlated with erythrocyte sedimentation rate. The cut-off values for PLR for predicting a sarcoidosis diagnosis were determined as 158.
CONCLUSION: Increase in PLR value can be used for guiding both the diagnosis of sarcoidosis and the involvement of parenchyma.