Oral surgery, oral medicine, oral pathology and oral radiology · 2013
Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Alam Sarwar, Ali Iqbal, Giri K Y, Gokkulakrishnan S, Natu Subodh S, Faisal Mohammad, Agarwal Anshita, Sharma Himanshu
Аннотация
OBJECTIVE: Definitive therapy is not defined for the management of oral submucous fibrosis (OSMF). This study evaluated the efficacy of aloe vera gel as an adjuvant treatment of OSMF.
STUDY DESIGN: A double-blind, placebo-controlled, parallel-group randomized controlled trial was conducted on 60 subjects with OSMF divided into medicinal treatment (submucosal injection of hyaluronidase and dexamethasone, n = 30) and surgical treatment (n = 30) categories. Each category was randomly divided into groups A (with aloe vera, n = 15 per category) and B (without aloe vera, n = 15 per category). Follow-up assessment for various symptoms was performed, and results were analyzed using paired and unpaired Student t tests.
RESULTS: The group receiving aloe vera had a significant improvement in most symptoms of OSMF (P < .01) compared with the non-aloe vera group, in both the medicinal and surgical categories.
CONCLUSIONS: Aloe vera gel was effective as an adjuvant in treatment of OSMF.
STUDY DESIGN: A double-blind, placebo-controlled, parallel-group randomized controlled trial was conducted on 60 subjects with OSMF divided into medicinal treatment (submucosal injection of hyaluronidase and dexamethasone, n = 30) and surgical treatment (n = 30) categories. Each category was randomly divided into groups A (with aloe vera, n = 15 per category) and B (without aloe vera, n = 15 per category). Follow-up assessment for various symptoms was performed, and results were analyzed using paired and unpaired Student t tests.
RESULTS: The group receiving aloe vera had a significant improvement in most symptoms of OSMF (P < .01) compared with the non-aloe vera group, in both the medicinal and surgical categories.
CONCLUSIONS: Aloe vera gel was effective as an adjuvant in treatment of OSMF.