Using toluidine blue as an adjunct to oral visual cancer screening among high-risk individuals may lead to increased detection of oral submucous fibrosis.

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: A community-based RCT for oral cancer screening with toluidine blue. Su WW, Yen AM, Chiu SY, Chen TH. J Dent Res 2010;89(9):933-7.

REVIEWER: Mark D. Macek, DDS, DrPH PURPOSE/QUESTION: Does using toluidine blue as an adjunctive tool for oral visual cancer screening lead to higher detection rates of oral premalignant lesions among high-risk populations?

SOURCE OF FUNDING: Information not available

TYPE OF STUDY/

DESIGN

Randomized controlled trial

LEVEL OF EVIDENCE: Level 2: Limited-quality, patient-oriented evidence

STRENGTH OF RECOMMENDATION GRADE: Not applicable.