Journal of the American Animal Hospital Association · 2007
Susceptibility of Pseudomonas isolates from the ears and skin of dogs to enrofloxacin, marbofloxacin, and ciprofloxacin.
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Wildermuth Brett Everett, Griffin Craig E, Rosenkrantz Wayne S, Boord Mona J
Аннотация
The purpose of this study was to compare susceptibilities of ear and skin Pseudomonas spp. isolates to enrofloxacin, marbofloxacin, and ciprofloxacin. Specimens were obtained from dogs examined in a veterinary dermatology referral hospital. Susceptibilities of ear isolates to enrofloxacin, marbofloxacin, and ciprofloxacin were 46.9%, 66.7%, and 75.0%, respectively. Susceptibilities of skin isolates to the same drugs were 76.2%, 81.0%, and 80.0%, respectively. Ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P=0.021), and ear isolates were significantly less susceptible to enrofloxacin than were skin isolates (P=0.034). When fluoroquinolone resistance was present, ear isolates were significantly less susceptible to enrofloxacin than to ciprofloxacin (P<0.001) and marbofloxacin (P=0.014).
Предметные рубрики MeSH
AnimalsAnti-Bacterial AgentsCiprofloxacinDog DiseasesDogsDose-Response Relationship, DrugDrug Resistance, BacterialEnrofloxacinFemaleFluoroquinolonesMaleMicrobial Sensitivity TestsOtitis ExternaPseudomonasPseudomonas InfectionsPyodermaQuinolonesRetrospective StudiesSkin Diseases, BacterialTreatment Outcome