Viral plasmacytosis (Aleutian disease) in mink. VI. The development of positive Coombs test in experimental infections.

Coombs tests became positive coincident with the development of plasmacytosis in experimentally infected mink. These observations are discussed as possible evidence of an auto-immune phenomenon. Several mechanisms are suggested in which a virus as primary etiologic agent might promote the observed plasmacytosis, hypergammaglobulinemia, and erythrocyte sensitization.