British medical journal (Clinical research ed.) · 1983
Immunological reason for chronic ill health after infectious mononucleosis.
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Hamblin T J, Hussain J, Akbar A N, Tang Y C, Smith J L, Jones D B
Аннотация
In a group of patients who suffered from chronic ill health after an attack of acute infectious mononucleosis a disorder of T cell regulation was found. By means of cytochemical reactions the staining pattern associated with T suppressor cells was found in a greater percentage and that associated with T helper cells in a smaller percentage than in normal subjects. In a few patients this finding was confirmed in a functional suppressor assay. The patients were unwell for at least a year but most later made a complete recovery, which was associated with return to normal of the lymphocyte subsets.