Late Recurrence of Metastatic Meningioma in the Lung in a Patient with Endometrial Cancer: A Case Report.

BACKGROUND Meningiomas are the most frequently diagnosed of all primary brain tumors, including glioblastomas, and of all other central nervous system tumors. While non-malignant meningiomas account for 36.7% of all primary brain tumors, malignant meningioma is much less common, accounting for just 0.6%. The annual incidence of meningiomas in the United States is 5.3 per 100 000 people. The median age of diagnosis is 64, and incidence rises steadily with advancing age. Furthermore, extracranial metastatic meningioma remains extremely rare (0.1%), with the most common location for metastasis being the lung. CASE REPORT We report a case of a patient with biopsy-proven endometrial adenocarcinoma with suspicious lung nodule, Stage IVB. She was managed with chemotherapy followed by surgery and radiation. During her course of management, she was found to have progressive pulmonary nodules. Later, biopsy from the pulmonary nodules showed a metastatic meningioma. CONCLUSIONS Our case highlights the importance of early recognition of metastatic meningioma, especially when treating patients with a history of intracranial meningioma.