Medical ultrasonography · 2014
Spectrum and prevalence of nodular thyroid diseases detected by ultrasonography in the Western Black Sea region of Turkey.
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Aydin Yusuf, Besir Fahri Halit, Erkan Melih Engin, Yazgan Omer, Gungor Adem, Onder Elif, Coşkun Hulya, Aydin Leyla
Аннотация
OBJECTIVE: The aim of the study was to investigate thyroid diseases and the prevalence of goiter by ultrasonography (US) in a moderately iodine deficient area.
MATERIAL-METHODS: The MELEN Study is a prospective cohort study on the prevalence of thyroid diseases in Turkish adults. A total of 2233 subjects with a mean age of 50 (age range 18 to 92) were submitted to study. Thyroid US was performed and interpreted by the same experienced physician. Goiter prevalence was defined according to Gutekunst's criteria.
RESULTS: The most common thyroid disease was multinodular goiter (MNG) (42%), followed by nodular goiter (NG) (14.6%). The crude prevalence of nodular disease in the region was 56.6%. In the study cohort, thyrotoxicosis (TSH <0.35 μIU/ml) prevalence was 12 % and subclinical and overt hypothyroidism (TSH > 4.5 μIU/ml) prevalence was 6.5 %.
CONCLUSION: We found that thyrotoxicosis and nodular thyroidal diseases are more important public health issues in moderate iodine deficient geographical areas. We recommend the increased rates of US screening especially in the endemic regions in order to detect thyroidal nodules earlier.
MATERIAL-METHODS: The MELEN Study is a prospective cohort study on the prevalence of thyroid diseases in Turkish adults. A total of 2233 subjects with a mean age of 50 (age range 18 to 92) were submitted to study. Thyroid US was performed and interpreted by the same experienced physician. Goiter prevalence was defined according to Gutekunst's criteria.
RESULTS: The most common thyroid disease was multinodular goiter (MNG) (42%), followed by nodular goiter (NG) (14.6%). The crude prevalence of nodular disease in the region was 56.6%. In the study cohort, thyrotoxicosis (TSH <0.35 μIU/ml) prevalence was 12 % and subclinical and overt hypothyroidism (TSH > 4.5 μIU/ml) prevalence was 6.5 %.
CONCLUSION: We found that thyrotoxicosis and nodular thyroidal diseases are more important public health issues in moderate iodine deficient geographical areas. We recommend the increased rates of US screening especially in the endemic regions in order to detect thyroidal nodules earlier.
Предметные рубрики MeSH
AdolescentAdultAgedAged, 80 and overBlack SeaCohort StudiesCross-Sectional StudiesEarly DiagnosisFemaleGoiter, EndemicGoiter, NodularHumansHypothyroidismIodineMaleMass ScreeningMiddle AgedOrgan SizeProspective StudiesSensitivity and SpecificityThyrotoxicosisThyrotropinThyroxineTurkeyUltrasonographyYoung Adult