The occurrence of Thomsen-Friedenreich receptors in bovine erythrocytes of various FV genotypes.

In the V/V type of bovine erythrocytes (BE), the antigen IM and the Thomsen-Friedenreich (TF) receptors, which reacted with a TF-specific agglutinin from human sera and the lectin from Helix pomatia, were all destroyed by treatment with trypsin. Unlike the V/V, in the F/F type of BE the antigen IM and these TF receptors were not only not destroyed by trypsin, but this enzyme treatment was, in fact, necessary to make them amenable to the corresponding agglutinins. Another TF receptor, which reacted with the lectin from peanuts, was identified on a trypsin-resistant component of all BE and independently of the FV genotypes.