New Finding in Vernal Keratoconjunctivitis: Splendore-Hoeppli Phenomenon.

PURPOSE: To report 2 cases of Splendore-Hoeppli phenomenon, a rare histopathologic observation, as a late clinical finding in vernal keratoconjunctivitis (VKC).

METHODS

We report the cases of 2 young women with subconjunctival nodules as a manifestation of Splendore-Hoeppli phenomenon with a history of severe VKC.

RESULTS

After eliminating other conditions causing such a reaction, both patients were treated using frequent topical corticosteroid, plus topical cyclosporine 2% in one of patient. Complete resolution was observed in both patients.

CONCLUSIONS

The Splendore-Hoeppli phenomenon could be a part of VKC manifestations.