Zhongguo shi yan xue ye xue za zhi · 2019
[Significance of Peripheral Blood Lymphatic to Monocyte Ratio in the Progress of PGI-DLBCL].
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Sun Ke-Meng, Sang Wei, Xu Lin-Yan, Yan Dong-Mei, Song Xu-Guang, Sun Cai, Sun Xiao-Kun, Xu Kai-Lin
Аннотация
OBJECTIVE: To explore the significance of lymphocyte to monocyte ratio (LMR) in the disease progress of primary gastrointestinal diffuse large B-cell lymphoma (PGI-DLBCL).
METHODS: The clinical data of 43 patients diagnosed as PGI-DLBCL in our hospital from January 2011 to December 2015 were collected, and the disease progress was followed up.
RESULTS: According to the ROC curve, the threshold value of LMR for 2 years PFS (%) of PGI-DLBCL patients was 2.6. Unvariate analysis showed that LMR (P＜0.05), large enclosed mass lesion (P＜0.01) and IPI (P＜0.05) were prognostic factors affecting PFS, the COX regression model multivariate analysis showed that LMR＜2.6 [ (risk ratio (RR)=3.083, 95%CI 1.828-8.313, P＜0.01], and large enclosed mass lesions (RR=2.718, 95%CI 1.339-6.424, P＜0.05) were the independent adverse prognostic factor for two years PFS.
CONCLUSION: Both LMR＜2.6 and large enclosed mass lesions relate with the progress of PGI-DLBCL.
METHODS: The clinical data of 43 patients diagnosed as PGI-DLBCL in our hospital from January 2011 to December 2015 were collected, and the disease progress was followed up.
RESULTS: According to the ROC curve, the threshold value of LMR for 2 years PFS (%) of PGI-DLBCL patients was 2.6. Unvariate analysis showed that LMR (P＜0.05), large enclosed mass lesion (P＜0.01) and IPI (P＜0.05) were prognostic factors affecting PFS, the COX regression model multivariate analysis showed that LMR＜2.6 [ (risk ratio (RR)=3.083, 95%CI 1.828-8.313, P＜0.01], and large enclosed mass lesions (RR=2.718, 95%CI 1.339-6.424, P＜0.05) were the independent adverse prognostic factor for two years PFS.
CONCLUSION: Both LMR＜2.6 and large enclosed mass lesions relate with the progress of PGI-DLBCL.