Zhongguo shi yan xue ye xue za zhi · 2016
[Manifestations of PET/CT Imaging in Primary Central Nervous System Lymphoma].
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yin Liang, Lin Zhi-Chun, Yue Jian-Lan, Huang Shi-Ming, Chen Wei
Аннотация
OBJECTIVE: To investigate the PET/CT features of primary central nervous system lymphoma(PCNSL).
METHODS: A retrospective analysis of PET/CT imaging manifestations and clinical data was performed in 4 PCNSL cases which were confirmed by surgery or stereotactic pathologic biopsy.
RESULTS: The pathologic biopsy in 4 patients all showed diffuse large B cell lymphoma with a total of 8 lesions. All cases were performed with 18F-FDG PET/CT imaging except 1 patient simultaneously with 18F-FLT PET/CT imaging in the brain. Single lesion was found in 2 cases which both were located in the left frontal lobe. Multiple lesions were found in 2 cases, out of them 1 case located in the corpus callosum and the right lateral ventricle Angle, and the other 1 located in dual lateral ventricle and pineal region. In 18F-FDG PET/CT image, 4 patients were characterized by high metabolism, even higher than the surrounding brain tissue. The patient which underwent 18F-FLT PET/CT imaging was also presented with high metabolism and had better Target and non-target ratio(T/N). 3 cases with surrounded by edema and 2 cases with area of cystic necrosis.
CONCLUSION: PCNSL are characterized by high metabolism in 18F-FDG PET/CT images and can better contrast with the surrounding normal brain. Combined use of other tracer such as 18F-FLT can improve the diagnostic value of PET/CT in PCNSL.
METHODS: A retrospective analysis of PET/CT imaging manifestations and clinical data was performed in 4 PCNSL cases which were confirmed by surgery or stereotactic pathologic biopsy.
RESULTS: The pathologic biopsy in 4 patients all showed diffuse large B cell lymphoma with a total of 8 lesions. All cases were performed with 18F-FDG PET/CT imaging except 1 patient simultaneously with 18F-FLT PET/CT imaging in the brain. Single lesion was found in 2 cases which both were located in the left frontal lobe. Multiple lesions were found in 2 cases, out of them 1 case located in the corpus callosum and the right lateral ventricle Angle, and the other 1 located in dual lateral ventricle and pineal region. In 18F-FDG PET/CT image, 4 patients were characterized by high metabolism, even higher than the surrounding brain tissue. The patient which underwent 18F-FLT PET/CT imaging was also presented with high metabolism and had better Target and non-target ratio(T/N). 3 cases with surrounded by edema and 2 cases with area of cystic necrosis.
CONCLUSION: PCNSL are characterized by high metabolism in 18F-FDG PET/CT images and can better contrast with the surrounding normal brain. Combined use of other tracer such as 18F-FLT can improve the diagnostic value of PET/CT in PCNSL.