[A survival analysis of 1761 nasopharyngeal carcinoma cases diagnosed during 1976-2005 in Sihui city in Guangdong province].

OBJECTIVES

To analyze the survival rate of nasopharyngeal carcinoma (NPC) and to evaluate the effect of intervention in this high risk population of NPC.

METHODS

Based on the cancer and vital registry systems, the follow-up data of 1761 NPC cases were collected. The measures of survival include 5-year, 10-year survival rate and median survival duration. Cox model was used to screen the independent prognosis factors.

RESULTS

The 5-year and 10-year survival rates of NPC cases in Sihui were 50.62% and 37.01%, and the median survival duration was 5.05 years. The survival rate of NPC cases diagnosed after 1993 was 58.8%, which was higher than that of cases diagnosed before 1993 (43.3%). Other prognosis factors included gender, age, clinical stage and diagnostic hospital.

CONCLUSION

There is a significant improvement of NPC survival in Sihui. That is mainly related to the improvement of NPC treatment. However, it needs to a long time observation to see a mortality reduction of NPC.