Altered proteome of a cystic fibrosis cell line model upon exposure to Pseudomonas aeruginosa biofilms.

Cystic fibrosis is associated with disruption of a key ion channel responsible for maintaining lung health. Upon disruption, fluids build within the lungs, creating a favorable environment for bacterial invasion. In this study, we assessed altered proteome regulation of a cystic fibrosis cell line model in response to bacterial biofilms.