Advances in skin & wound care · 2015
Pulsed electromagnetic field therapy promotes healing and microcirculation of chronic diabetic foot ulcers: a pilot study.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Kwan Rachel Lai-Chu, Wong Wing-Cheung, Yip Siu-Leung, Chan Ka-Lun, Zheng Yong-Ping, Cheing Gladys Lai-Ying
Аннотация
OBJECTIVE: To examine the effects of pulsed electromagnetic field (PEMF) therapy on promoting the healing and microcirculation of chronic diabetic foot ulcers.
DESIGN: A randomized, double-blind, placebo-controlled clinical trial on a homogenous subset of chronic diabetic foot ulcers.
SETTING: Hospital and university.
PATIENTS: Thirteen subjects (7 in the PEMF group and 6 in the control group) diagnosed with type 2 diabetes and had unsatisfactory healing of ulcer(s) in the preceding 4 weeks were recruited.
INTERVENTIONS: Subjects were randomly allocated to receive either active PEMF therapy (duration: 60 minutes; frequency: 12 Hz; intensity: 12 Gauss) or nonactive PEMF for 14 sessions within 3 weeks.
MAIN OUTCOME MEASURES: Assessment on wound closure, wound depth, and microcirculation were performed at the baseline, end of the treatment period, and 1-month follow-up.
MAIN RESULTS: By the end of the treatment period, there was an 18% decrease in wound size in the active PEMF group as compared with a 10% decrease in the control group. The PEMF group demonstrated significant cumulative increase in cutaneous capillary blood velocity (by 28%) and 14% increase in capillary diameter. In contrast, the control group showed a decrease in both capillary blood velocity and diameter.
CONCLUSION: In this study, PEMF therapy seemed to accelerate wound healing and improve microcirculation.
DESIGN: A randomized, double-blind, placebo-controlled clinical trial on a homogenous subset of chronic diabetic foot ulcers.
SETTING: Hospital and university.
PATIENTS: Thirteen subjects (7 in the PEMF group and 6 in the control group) diagnosed with type 2 diabetes and had unsatisfactory healing of ulcer(s) in the preceding 4 weeks were recruited.
INTERVENTIONS: Subjects were randomly allocated to receive either active PEMF therapy (duration: 60 minutes; frequency: 12 Hz; intensity: 12 Gauss) or nonactive PEMF for 14 sessions within 3 weeks.
MAIN OUTCOME MEASURES: Assessment on wound closure, wound depth, and microcirculation were performed at the baseline, end of the treatment period, and 1-month follow-up.
MAIN RESULTS: By the end of the treatment period, there was an 18% decrease in wound size in the active PEMF group as compared with a 10% decrease in the control group. The PEMF group demonstrated significant cumulative increase in cutaneous capillary blood velocity (by 28%) and 14% increase in capillary diameter. In contrast, the control group showed a decrease in both capillary blood velocity and diameter.
CONCLUSION: In this study, PEMF therapy seemed to accelerate wound healing and improve microcirculation.