Journal of cataract and refractive surgery · 1997
Association between nonadministration of subconjunctival cefuroxime and postoperative endophthalmitis.
Клиническое исследованиеСтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Lehmann O J, Roberts C J, Ikram K, Campbell M J, McGill J I
Аннотация
PURPOSE: To determine whether not administering subconjunctival cefuroxime during cataract surgery is associated with postoperative endophthalmitis.
SETTING: Southampton Eye Unit, Southampton General Hospital, England.
METHODS: This retrospective, case-control study comprised nine patients who developed endophthalmitis after cataract surgery in a single ophthalmic unit over a 21 month period. Ten control patients for each case were randomly chosen from patients having cataract surgery within 1 week of the endophthalmitis case.
RESULTS: None of the nine endophthalmitis patients received peroperative subconjunctival cefuroxime compared with 43 of 90 control patients (47.8%) (P = 0.008). No other variables were found to be associated with development of endophthalmitis in this study.
CONCLUSION: Nonadministration of subconjunctival cefuroxime was associated with subsequent endophthalmitis. A further study to determine whether the observed association is causal is therefore warranted.
SETTING: Southampton Eye Unit, Southampton General Hospital, England.
METHODS: This retrospective, case-control study comprised nine patients who developed endophthalmitis after cataract surgery in a single ophthalmic unit over a 21 month period. Ten control patients for each case were randomly chosen from patients having cataract surgery within 1 week of the endophthalmitis case.
RESULTS: None of the nine endophthalmitis patients received peroperative subconjunctival cefuroxime compared with 43 of 90 control patients (47.8%) (P = 0.008). No other variables were found to be associated with development of endophthalmitis in this study.
CONCLUSION: Nonadministration of subconjunctival cefuroxime was associated with subsequent endophthalmitis. A further study to determine whether the observed association is causal is therefore warranted.