Frontiers in oral health · 2026
Effect of minimally invasive non-surgical periodontal therapy in former smokers with periodontitis on salivary IL-1β and PGE-2 profile.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Elshiaty Noura Mohamed, Al-Zubaidi Saad Mohammad, El Demerdash Fatma Hamed, Elkholy Hussien, Gamal Ahmed Youssef
Аннотация
OBJECTIVES: Limited data are available regarding salivary inflammatory marker levels following conventional versus minimally invasive non-surgical periodontal therapy and smoking cessation. This study aimed to evaluate the effects of conventional non-surgical periodontal therapy (CNST) versus minimally invasive non-surgical periodontal therapy (MINST) on the levels of salivary inflammatory markers, specifically interleukin-1β (IL-1β) and prostaglandin E2 (PGE2), in patients with stage III grade A/B periodontitis. Moreover, it investigated the impact of smoking cessation on these biomarkers and compared outcomes among smokers, non-smokers (NS), and individuals who quit smoking.
METHODS: A randomized controlled biochemical trial was conducted with 40 patients divided into four groups: smokers who quit and received conventional therapy (SQ1), smokers who quit and received minimally invasive therapy (SQ2), smokers continuing to smoke (SC), and NS.
RESULTS: Both the SQ2 and NS groups reported significant reductions in salivary PGE2 and IL-1β levels at both observation periods compared with the SC group.
CONCLUSIONS: MINST appeared more effective in controlling inflammatory markers among patients who quit smoking compared with conventional non-surgical therapy.
METHODS: A randomized controlled biochemical trial was conducted with 40 patients divided into four groups: smokers who quit and received conventional therapy (SQ1), smokers who quit and received minimally invasive therapy (SQ2), smokers continuing to smoke (SC), and NS.
RESULTS: Both the SQ2 and NS groups reported significant reductions in salivary PGE2 and IL-1β levels at both observation periods compared with the SC group.
CONCLUSIONS: MINST appeared more effective in controlling inflammatory markers among patients who quit smoking compared with conventional non-surgical therapy.