[Extranodal T/NK-cell lymphoma, nasal type: a case report and review of the literature].

Extranodal T/NK-cell lymphoma, nasal type: a case report and review of the literature. Extranodal NK/T-cell lymphoma, nasal type, is an extranodal lymphoma, usually with an NK-cell phenotype and EBV positive, with a broad morphologic spectrum, frequent necrosis and angioinvasion, and most commonly presenting in the midfacial region, but also in other extranodal sites. We present the case of a 42-years old-man with a intranasal mass, left cervical adenopathies and indolent thrombocytosis. The biopsy of the nasal mass showed a diffuse infiltrate of medium-sized lymphoid cells, with slightly irregular nuclei and moderate polymorphous. The immunophenotype of tumor cells was CD45+, cCD3+, Granzyme B+, CD56+, CD20-,CD4-,CD8-, LMP1(EBV)-. The diagnosis of the case was Extranodal T/NK-cell lymphoma, nasal type. There was not disseminated disease in the extent studies. With the diagnosis of localized extranodal T/NK-cell lymphoma and reactive thrombocytosis, the patient was treated with chemotherapy and sequential radiotherapy, followed by bone marrow transplantation.