Vascular · 2013
Carotid endarterectomy in the elderly: risk factors, intraoperative carotid hemodynamics and short-term complications: a UK tertiary center retrospective analysis.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Sadideen H, Thomson D R, Lewis R R, Padayachee T S, Taylor P R
Аннотация
This retrospective analysis aims to demonstrate the safety of carotid endarterectomy (CE) in patients >75 years with particular attention paid to intraoperative hemodynamics. Four hundred and ninety-six consecutive patients with >70% symptomatic and asymptomatic stenosis who underwent CE were prospectively assessed and divided into those <75 years (n = 408; mean 64 years) and those >75 years (n = 88; mean 78 years). Associated risk factors, hemodynamic parameters, surgical techniques and 30-day perioperative complications were compared. Carotid artery stump pressures of <25 mmHg (13 versus 29%) and middle cerebral artery velocities of <20 cm/sec (46 versus 29%) were more common in those >75 years (P = 0.0001 and P <0.005, respectively). However, there was no difference in the frequency of intraluminal shunt (34% in both groups) or synthetic patch usage (primary patching: 12.5%, older group versus 11%, younger group; secondary patching: 34% in both groups), and no difference in the combined 30-day stroke and death rates (3.4%, >75 years versus 1.1%, <75 years; P = 0.425). CE in this cohort of patients >75 years was not associated with increased morbidity or mortality. Altered intraoperative hemodynamics were not associated with increased use of shunting or patching. This analysis supports CE as a safe procedure in the elderly.
Предметные рубрики MeSH
Age FactorsAgedAged, 80 and overArterial PressureAsymptomatic DiseasesBlood Flow VelocityCarotid ArteriesCarotid StenosisCerebrovascular CirculationDatabases, FactualEndarterectomy, CarotidFemaleHemodynamicsHumansLondonMaleMiddle AgedMiddle Cerebral ArteryRetrospective StudiesRisk FactorsStrokeTertiary Care CentersTime FactorsTreatment Outcome