Current opinion in infectious diseases · 2020
Unresolved issues in the identification and treatment of carbapenem-resistant Gram-negative organisms.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kois Abigail K, Nicolau David P, Kuti Joseph L
Аннотация
PURPOSE OF REVIEW: Carbapenem-resistant organisms (CROs), including Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacterales, are a threat worldwide. This review will cover mechanisms of resistance within CROs and challenges with identification and treatment of these organisms while pointing out unresolved issues and ongoing challenges.
RECENT FINDINGS: The treatment of CROs has expanded through newer therapeutic options. Guided utilization through genotypic and phenotypic testing is necessary in order for these drugs to target the appropriate mechanisms of resistance and select optimal antibiotic therapy.
SUMMARY: Identification methods and treatment options need to be precisely understood in order to limit the spread and maximize outcomes of CRO infections.
RECENT FINDINGS: The treatment of CROs has expanded through newer therapeutic options. Guided utilization through genotypic and phenotypic testing is necessary in order for these drugs to target the appropriate mechanisms of resistance and select optimal antibiotic therapy.
SUMMARY: Identification methods and treatment options need to be precisely understood in order to limit the spread and maximize outcomes of CRO infections.
Предметные рубрики MeSH
Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsCarbapenemsColistinDrug Resistance, Multiple, BacterialEnterobacteriaceaeGenotyping TechniquesGram-Negative Bacterial InfectionsHumansMicrobial Sensitivity TestsPseudomonas aeruginosabeta-Lactam Resistancebeta-Lactamase Inhibitorsbeta-Lactamasesbeta-Lactams