Tremor and other hyperkinetic movements (New York, N.Y.) · 2017
High-voltage VIM Region Deep Brain Stimulation Mimicking Progressive Supranuclear Palsy.
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Patterson Addie, Okun Michael S, Hess Christopher
Аннотация
BACKGROUND: Deep brain stimulation (DBS) for essential tremor (ET) can cause unwanted side effects.
CASE REPORT: A patient with ET underwent unilateral dual-lead thalamic DBS. He later developed parkinsonism with atypical features and was diagnosed with progressive supranuclear palsy. During presentation for a second opinion, stimulation-induced side effects were suspected. Inactivation of DBS resolved atypical features and superimposed idiopathic Parkinson disease (PD) was diagnosed.
DISCUSSION: This case illustrates the importance of recognizing the possible influence of stimulation-induced side effects and discusses when to utilize dual-lead DBS for ET and the co-occurrence of ET and PD.
CASE REPORT: A patient with ET underwent unilateral dual-lead thalamic DBS. He later developed parkinsonism with atypical features and was diagnosed with progressive supranuclear palsy. During presentation for a second opinion, stimulation-induced side effects were suspected. Inactivation of DBS resolved atypical features and superimposed idiopathic Parkinson disease (PD) was diagnosed.
DISCUSSION: This case illustrates the importance of recognizing the possible influence of stimulation-induced side effects and discusses when to utilize dual-lead DBS for ET and the co-occurrence of ET and PD.