Immunotherapy · 2020
Clinical impact of COVID-19 in a single-center cohort of a prospective study in cancer patients receiving immunotherapy.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Bersanelli Melissa, Zielli Teresa, Perrone Fabiana, Casartelli Chiara, Pratticò Fabiana, Rapacchi Elena, Camisa Roberta, Tognetto Michele, Clemente Alberto, Giannarelli Diana, Rebuzzi Sara Elena, Leonetti Alessandro, Bordi Paola, Tiseo Marcello, Buti Sebastiano
Аннотация
Aim: Evaluating the incidence and course of COVID-19 in cancer patients treated with immunotherapy. Patients & methods: We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma. Results: Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. They were males, elderly, with cardiovascular disease. Radiological features of COVID-19 pneumonitis were found in all of three cases, although the pharyngeal swab resulted positive in only two. Two of these three patients died due to respiratory failure. Conclusion: Cancer patients are at high risk of severe events from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.