Histiocytic medullary reticulosis: a report of four cases from India.

Four cases of histiocytic medullary reticulosis encountered between 1968 and 1972 at the All-India Institute of Medical Sciences Hospital, New Delhi, are reported. One of the cases was diagnosed during life and the other three postmortem. A complete remission was achieved in the former following prednisolone and cyclophosphamide therapy. The histological changes consisted of malignant histiocytosis with erythrophagocytosis in the organs of the reticuloendothelial system. The lymph nodes and the bone marrow were involved in all the cases. The importance of biopsy examination of these organs in making an early diagnosis is emphasised.