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DOI 10.1055/s-0040-1708035

Медицинская библиотека · Thrombosis and haemostasis · 2020

Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis.

d'Alessandro Elisa, Becker Christian, Bergmeier Wolfgang, Bode Christoph, Bourne Joshua H, Brown Helena, Buller Harry R, Ten Cate-Hoek Arina J, Ten Cate Vincent, van Cauteren Yvonne J M, Cheung Yam F H, Cleuren Audrey, Coenen Danielle, Crijns Harry J G M, de Simone Ilaria, Dolleman Sophie C, Klein Christine Espinola, Fernandez Delia I, Granneman Lianne, van T Hof Arnoud, Henke Peter, Henskens Yvonne M C, Huang Jingnan, Jennings Lisa K, Jooss Natalie, Karel Mieke, van den Kerkhof Danique, Klok Frederik A, Kremers Bram, Lämmle Bernhard, Leader Avi, Lundstrom Annika, Mackman Nigel, Mannucci Pier M, Maqsood Zahra, van der Meijden Paola E J, van Moorsel Marc, Moran Luis A, Morser John, van Mourik Manouk, Navarro Stefano, Neagoe Raluca A I, Olie Renske H, van Paridon Pauline, Posma Jens, Provenzale Isabella, Reitsma Pieter H, Scaf Billy, Schurgers Leon, Seelig Jaap, Siegbahn Agneta, Siegerink Bob, Soehnlein Oliver, Soriano Eva Maria, Sowa Marcin A, Spronk Henri M H, Storey Robert F, Tantiwong Chukiat, Veninga Alicia, Wang Xueqing, Watson Steve P, Weitz Jeff, Zeerleder Sacha S, Ten Cate Hugo, Scientific Reviewer Committee

Consensus StatementСтатьяПеревод пока не подготовлен

Аннотация

Thrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The third Maastricht Consensus Conference on Thrombosis assembled basic, translational, and clinical scientists to discuss the origin and potential consequences of thrombo-inflammation in the etiology, diagnostics, and management of patients with cardiovascular disease, including myocardial infarction, stroke, and peripheral artery disease. This article presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following topics: (1) challenges of the endothelial cell barrier; (2) circulating cells and thrombo-inflammation, focused on platelets, neutrophils, and neutrophil extracellular traps; (3) procoagulant mechanisms; (4) arterial vascular changes in atherogenesis; attenuating atherosclerosis and ischemia/reperfusion injury; (5) management of patients with arterial vascular disease; and (6) pathogenesis of venous thrombosis and late consequences of venous thromboembolism.

Для цитирования: d'Alessandro Elisa, Becker Christian, Bergmeier Wolfgang, Bode Christoph, Bourne Joshua H, Brown Helena, Buller Harry R, Ten Cate-Hoek Arina J, Ten Cate Vincent, van Cauteren Yvonne J M, Cheung Yam F H, Cleuren Audrey, Coenen Danielle, Crijns Harry J G M, de Simone Ilaria, Dolleman Sophie C, Klein Christine Espinola, Fernandez Delia I, Granneman Lianne, van T Hof Arnoud, Henke Peter, Henskens Yvonne M C, Huang Jingnan, Jennings Lisa K, Jooss Natalie, Karel Mieke, van den Kerkhof Danique, Klok Frederik A, Kremers Bram, Lämmle Bernhard, Leader Avi, Lundstrom Annika, Mackman Nigel, Mannucci Pier M, Maqsood Zahra, van der Meijden Paola E J, van Moorsel Marc, Moran Luis A, Morser John, van Mourik Manouk, Navarro Stefano, Neagoe Raluca A I, Olie Renske H, van Paridon Pauline, Posma Jens, Provenzale Isabella, Reitsma Pieter H, Scaf Billy, Schurgers Leon, Seelig Jaap, Siegbahn Agneta, Siegerink Bob, Soehnlein Oliver, Soriano Eva Maria, Sowa Marcin A, Spronk Henri M H, Storey Robert F, Tantiwong Chukiat, Veninga Alicia, Wang Xueqing, Watson Steve P, Weitz Jeff, Zeerleder Sacha S, Ten Cate Hugo, Scientific Reviewer Committee. Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis.. Thrombosis and haemostasis. 2020. DOI: 10.1055/s-0040-1708035.

Предметные рубрики MeSH

AnimalsAtherosclerosisBlood CoagulationCardiovascular DiseasesEndothelium, VascularHumansImmunity, InnateInflammationNeutrophilsThrombosisVenous Thromboembolism
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