Hepato-gastroenterology · 2002
Lower specificity of occult-blood test on stool collected by digital rectal examination.
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Zhang Bing, Nakama Hidenori, Fattah A S M Abdul, Kamijo Noboru
Аннотация
BACKGROUND/AIMS: To compare the diagnostic accuracy of an immunochemical fecal occult-blood test for colorectal cancer between the stool specimens obtained during the routine screening and those during the digital rectal examination.
METHODOLOGY: One hundred and fourteen patients with colorectal cancer and 228 healthy controls served as subjects of the study. Fecal occult-blood was tested by both of two methods; by the routine screening and by the digital rectal examination, and the sensitivity and specificity of an immunochemical fecal occult-blood test were determined in these two methods.
RESULTS: The sensitivity and specificity were 79.8% and 96.5% in the routine screening method, and 86.0% and 79.8% in the digital rectal examination method, respectively, showing a significant difference in the specificity (P < 0.01) between these two stool collection methods. There was no significant difference in the sensitivity between these two stool collection methods.
CONCLUSIONS: These findings indicate that the stool specimens collected at the time of the digital rectal examination is not suitable for testing of fecal occult-blood.
METHODOLOGY: One hundred and fourteen patients with colorectal cancer and 228 healthy controls served as subjects of the study. Fecal occult-blood was tested by both of two methods; by the routine screening and by the digital rectal examination, and the sensitivity and specificity of an immunochemical fecal occult-blood test were determined in these two methods.
RESULTS: The sensitivity and specificity were 79.8% and 96.5% in the routine screening method, and 86.0% and 79.8% in the digital rectal examination method, respectively, showing a significant difference in the specificity (P < 0.01) between these two stool collection methods. There was no significant difference in the sensitivity between these two stool collection methods.
CONCLUSIONS: These findings indicate that the stool specimens collected at the time of the digital rectal examination is not suitable for testing of fecal occult-blood.