Ocular oncology and pathology · 2015
Orbital Paraganglioma and Succinate Dehydrogenase Staining for Genetic Testing Triage and Prognosis.
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Salinas-La Rosa Cesar M
Аннотация
PURPOSE OF THE STUDY: To describe the rare occurrence of a paraganglioma in the orbit and how to triage for genetic testing and assess the prognosis with succinate dehydrogenase subunit B (SDHB) immunohistochemical staining.
METHOD: Case report.
PROCEDURES: A 47-year-old 'Работает' male presented with painless exophthalmos and diplopia secondary to an infraorbital tumour mass.
RESULTS: The orbital biopsy was diagnosed as paraganglioma with positive staining with SDHB.
CONCLUSION: The rarity of an orbital paraganglioma was followed by the clinical search for a possible occult extraorbital primary paraganglioma. SDHB staining helped in the triage for genetic testing and gave an idea about the prognosis for this tumour.
METHOD: Case report.
PROCEDURES: A 47-year-old 'Работает' male presented with painless exophthalmos and diplopia secondary to an infraorbital tumour mass.
RESULTS: The orbital biopsy was diagnosed as paraganglioma with positive staining with SDHB.
CONCLUSION: The rarity of an orbital paraganglioma was followed by the clinical search for a possible occult extraorbital primary paraganglioma. SDHB staining helped in the triage for genetic testing and gave an idea about the prognosis for this tumour.