THE EXPERIMENTAL PRODUCTION IN DOGS OF ACUTE STOMATITIS, ASSOCIATED WITH LEUCOPENIA AND A MATURATION DEFECT OF THE MYELOID ELEMENTS OF THE BONE MARROW.

An ulcerative stomatitis associated with leucopenia and granulopenia can be induced in dogs by means of a diet causing black tongue. The decrease of circulating leucocytes is due to a suppression of maturation of the erythropoietic elements of the bone marrow. The changes as a whole have a resemblance to those occurring in human beings with acute agranulocytosis.