Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017
A Longitudinal Follow-Up Study on Multiple Sleep Latency Test and Body Mass Index of Patients With Narcolepsy Type 1 in Korea.
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Um Yoo Hyun, Kim Tae-Won, Jeong Jong-Hyun, Seo Ho-Jun, Han Jin-Hee, Kim Sung-Min, Song Ji Hyun, Hong Seung-Chul
Аннотация
STUDY OBJECTIVES: Narcolepsy is a chronic disorder with numerous adverse long-term consequences including increased obesity, high mortality rates, and decreased quality of life. With emerging attention to the long-term course of the disorder and importance of accurate diagnosis, the diagnostic stability of the Multiple Sleep Latency Test (MSLT)-the mostly frequently used test to identify narcolepsy-is often challenged.
METHODS: In this study, we compared the baseline and follow-up demographic characteristics and body mass index (BMI) of patients with narcolepsy type 1. Moreover, MSLT results from repeated tests conducted on 48 patients with narcolepsy type 1 were compared, with mean follow-up of approximately 10 years.
RESULTS: BMI from the baseline to the follow-up visit was significantly increased in the participants. There were no significantly different parameter changes in MSLT results.
CONCLUSIONS: MSLT has good test-retest validity in patients with narcolepsy type 1. Close surveillance for the detection and management of obesity is warranted in clinical settings.
METHODS: In this study, we compared the baseline and follow-up demographic characteristics and body mass index (BMI) of patients with narcolepsy type 1. Moreover, MSLT results from repeated tests conducted on 48 patients with narcolepsy type 1 were compared, with mean follow-up of approximately 10 years.
RESULTS: BMI from the baseline to the follow-up visit was significantly increased in the participants. There were no significantly different parameter changes in MSLT results.
CONCLUSIONS: MSLT has good test-retest validity in patients with narcolepsy type 1. Close surveillance for the detection and management of obesity is warranted in clinical settings.