Initial therapy of suspected microbial corneal ulcers. II. Specific antibiotic therapy based on corneal smears.

The encounter of the microorganism with the cornea is a complex event which generates tissue destruction through multiple host and organism-derived mediators. Suspicion of microbial invasion, proper utilization of the microbiology laboratory, and initiation of effective antimicrobial agents are the crucial measures in controlling the replicating organism and preserving visual function.