Archives of dermatology · 1994
Recurrence of pemphigus vulgaris associated with interleukin 2 therapy.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Prussick R, Plott R T, Stanley J R
Аннотация
BACKGROUND: Immunotherapy with recombinant interleukin 2 may result in regression of metastatic cancer, particularly malignant melanoma and renal cell carcinoma.
OBSERVATIONS: We describe a patient who received interleukin 2 immunotherapy for metastatic renal cell carcinoma. After his second course of treatment, he developed a recurrence of pemphigus vulgaris that had been in remission for 10 years.
CONCLUSIONS: Interleukin 2 therapy may be associated with recurrence of an autoimmune disease, perhaps because of its ability to stimulate autoantibody production.
OBSERVATIONS: We describe a patient who received interleukin 2 immunotherapy for metastatic renal cell carcinoma. After his second course of treatment, he developed a recurrence of pemphigus vulgaris that had been in remission for 10 years.
CONCLUSIONS: Interleukin 2 therapy may be associated with recurrence of an autoimmune disease, perhaps because of its ability to stimulate autoantibody production.