[CME: Primary Hyperparathyroidism].

CME: Primary Hyperparathyroidism Abstract. In most cases, primary hyperparathyroidism (pHPT) is accidentally diagnosed when hypercalcemia is detected in a routine blood test. At the time of diagnosis, most patients do not have symptoms, although they may already have skeletal and renal sequelae. This article particularly elucidates the diagnostic steps of pHPT and the monitoring of patients with asymptomatic pHPT. As nowadays parathyroid hormone (PTH) is often measured without previously diagnosed hypercalcemia, we separately discuss the isolated PTH elevation and its most common causes.