[Drug-induced skin reactions].

Antimicrobials and anti-inflammatories are the most common drugs causing skin reactions, but reactions are also brought about by ACE inhibitors, antiepileptics, many anticancer and certain other drugs. Exanthema and urticaria are the most common types of drug reactions. Urticaria may or may not be accompanied by angioedema or anaphylaxia. Possible life-threatening drug reactions include also toxic epidermal necrolysis, Stevens-Johnson syndrome and eosinophilia with systemic symptoms. A drug reaction resembles a typical allergic reaction. Diagnosis is based on the clinical picture and anamnesis.