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DOI 10.1007/s00784-025-06189-5

Медицинская библиотека · Clinical oral investigations · 2025

Piano level laser therapy versus epidermal growth factor injection for painful myogenic temporomandibular disorder (a randomized clinical trial).

Qataya Passant Osama, Zaki Azza Mohamed, Amin Fatma, Swedan Ahmed, Elkafrawy Hagar

СтатьяРандомизированное исследованиеПеревод пока не подготовлен

Аннотация

OBJECTIVE

The aim of this clinical trial was to evaluate the effectiveness of Piano level laser therapy using Nd-YAG laser and intramuscular EGF injection in pain alleviation, function, and quality of life improvement in patients suffering from myogenic TMD.

MATERIALS AND

METHODS

A randomized clinical trial was performed on 29 patients suffering from chronic painful myogenic TMD based on diagnostic criteria for temporomandibular disorders. Group I (n = 13patients) was treated using 1064 nm Nd-YAG Laser (4 sessions once/week). Group II (n = 14 patients) was treated by intramuscular injection of EGF. Pain using numerical rating score, pain free opening and unassisted maximum opening were measured at baseline, 7,14,21 days, 1 and 3 months. Quality of life using OHIP-14 was assessed at baseline, 1 and 3 months.

RESULTS

Results showed that there was a significant pain reduction (P < 0.000) and increase in pain free opening (P < 0.0001) in both test groups. However, only group I showed a significant increase in maximum opening (P = 0.007). Quality of life significantly improved in both groups (P = 0.0001). There was no significant difference between the two treatments in pain scores, pain free opening, maximum opening nor quality of life.

CONCLUSION

Both treatment modalities offered effective and cost-effective non- to minimally invasive treatment options for myogenic TMD with no side effects.

CLINICAL RELEVANCE: Myogenic TMD forms a public health issue and is a common musculoskeletal problem causing pain and disability. The proposal of effective, non-invasive, and affordable treatment options can help solve this issue.

Для цитирования: Qataya Passant Osama, Zaki Azza Mohamed, Amin Fatma, Swedan Ahmed, Elkafrawy Hagar. Piano level laser therapy versus epidermal growth factor injection for painful myogenic temporomandibular disorder (a randomized clinical trial).. Clinical oral investigations. 2025. DOI: 10.1007/s00784-025-06189-5.

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