Journal of affective disorders · 2018
Methemoglobinemia as a biomarker of dapsone-induced mania severity.
Клинический случайПисьмо в редакциюНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Colle Romain, Ait Tayeb Abd El Kader, Mesdom Pierre, de Menthon Mathilde, Becquemont Laurent, Verstuyft Céline, David Denis J, Lambotte Olivier, Corruble Emmanuelle
Аннотация
BACKGROUND: The underlying mechanism involved in dapsone-induced mania remains unknown.
METHODS: We report the case of a 54-year-old man with a dapsone-induced mania.
RESULTS: The maximum of manic symptoms was correlated with the maximum of methemoglobinemia and mania decreased concomitantly with the methemoglobinemia level.
LIMITATIONS: This is a single case.
CONCLUSIONS: This case shows that dapsone-induced mania severity is correlated with methemoglobinemia level, leading for the first time to the hypothesis of a physiopathological mechanism by which dapsone could induce mania.
METHODS: We report the case of a 54-year-old man with a dapsone-induced mania.
RESULTS: The maximum of manic symptoms was correlated with the maximum of methemoglobinemia and mania decreased concomitantly with the methemoglobinemia level.
LIMITATIONS: This is a single case.
CONCLUSIONS: This case shows that dapsone-induced mania severity is correlated with methemoglobinemia level, leading for the first time to the hypothesis of a physiopathological mechanism by which dapsone could induce mania.