Journal of affective disorders · 2026
Parental absence and suicidal ideation in depressed adolescents: Differential mediating roles of father-child vs. mother-child relationships and the moderating effect of sex.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Wang Yang, Huang Bingxue, Zou Xinwen, Zhu Zhenzhen, Zhang Qi, Zhou Yongjie
Аннотация
BACKGROUND: Parental absence is a significant risk factor for adolescent suicidal ideation, yet the relational mechanisms and sex-specific vulnerabilities within clinical populations remain under-explored. This study investigated how different forms of parental absence relate to suicidal ideation through father-child and mother-child relationships, and whether these associations are moderated by adolescent sex.
METHODS: A nationwide multi-center cross-sectional study was conducted from December 2020 to December 2023. We recruited 2467 clinically diagnosed depressed adolescents from 14 hospitals in China. A moderated mediation model was tested using Firth's penalized logistic regression to address outcome imbalance. The model explicitly disaggregated single-parent and dual-parent absence while testing sex as a moderator of direct pathways.
RESULTS: A significant interaction between sex and single-parent absence emerged, indicating single-parent absence was associated with higher suicidal ideation specifically among female adolescents (B = 1.144, p = 0.011). Mediation analyses demonstrated that the father-child relationship served as a consistent mediator for both single-parent (indirect effect = 0.058, 95% CI [0.003, 0.129]) and dual-parent absence (indirect effect = 0.066, 95% CI [0.004, 0.151]). Conversely, the mother-child relationship showed no significant mediating effect after adjustment.
LIMITATIONS: The cross-sectional design limits causal inferences, and certain variables were assessed using self-report single-item measures.
CONCLUSIONS: Parental absence influences suicidal ideation through distinct structural and relational pathways. The father-child relationship emerged as a more robust mediator than the mother-child relationship, while sex moderated the direct impact of family disruption. These results highlight the necessity of sex-sensitive and father-inclusive clinical interventions in preventing suicide among depressed adolescents.
METHODS: A nationwide multi-center cross-sectional study was conducted from December 2020 to December 2023. We recruited 2467 clinically diagnosed depressed adolescents from 14 hospitals in China. A moderated mediation model was tested using Firth's penalized logistic regression to address outcome imbalance. The model explicitly disaggregated single-parent and dual-parent absence while testing sex as a moderator of direct pathways.
RESULTS: A significant interaction between sex and single-parent absence emerged, indicating single-parent absence was associated with higher suicidal ideation specifically among female adolescents (B = 1.144, p = 0.011). Mediation analyses demonstrated that the father-child relationship served as a consistent mediator for both single-parent (indirect effect = 0.058, 95% CI [0.003, 0.129]) and dual-parent absence (indirect effect = 0.066, 95% CI [0.004, 0.151]). Conversely, the mother-child relationship showed no significant mediating effect after adjustment.
LIMITATIONS: The cross-sectional design limits causal inferences, and certain variables were assessed using self-report single-item measures.
CONCLUSIONS: Parental absence influences suicidal ideation through distinct structural and relational pathways. The father-child relationship emerged as a more robust mediator than the mother-child relationship, while sex moderated the direct impact of family disruption. These results highlight the necessity of sex-sensitive and father-inclusive clinical interventions in preventing suicide among depressed adolescents.