[Urologic manifestations in Wolfram's syndrome].

The association of insipidus diabetes, diabetes mellitus, optic atrophy and deafness is known as the Wolfram syndrome. This paper contributes two case reports with significant urological sings and symptoms associated (ureterohydronephrosis, neurogenic bladder) both studied from a radiological and urodynamic point of view, with comments on the probable origin of the urological alternatives as well as their evolution, which was favourable after treatment with antibiotics and intermittent vesical catheterism.