Optical mapping of prefrontal activity in pathological gamblers.

Functional near-infrared spectroscopy (fNIRS) has emerged as a highly promising brain mapping technique that enables continuously and noninvasively monitoring the hemodynamic responses in the human brain. In this study, fNIRS was utilized to identify the different brain activation patterns between pathological gamblers (PGs) and healthy controls (HCs). Specifically, we examined the hemodynamic changes in the prefrontal cortex using fNIRS recordings during the completion of executive function and decision-making tasks for both PGs and HCs. Our mapping results revealed that PGs and HCs exhibited notable differences in the hemodynamic responses and brain activation patterns across the prefrontal region.