Enfermedades infecciosas y microbiologia clinica (English ed.) · 2026
Clinical evaluation of a rapid antigen detection test for the diagnosis of tinea unguium.
СтатьяОценочное исследованиеСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Argente-Colás Lucía, Urmeneta Miren, Hernán-Gómez Sayoa, Navascués-Ortega Ana, Portillo María-Eugenia, Fernández-Huerta Miguel
Аннотация
INTRODUCTION: Currently, diagnosis of dermatophyte onychomycosis relies on direct microscopic examination (DME) and fungal cultures of nail material. Herein, we aim to evaluate the clinical performance of the rapid antigen detection (RAD) assay PreventID Dermatophyte in comparison to conventional methods for the diagnosis of tinea unguium.
METHODS: Between February and July 2024, 48 nail samples, collected at the Navarra University Hospital, Spain, were included in the evaluation. In addition to DME and culture, the RAD test was executed. In case of discrepancies, the qPCR assay Novaplex™ Dermatophyte was utilized.
RESULTS: Overall, the RAD test performed well, comparable to DME or culture, with concordances of 80.9% and 80.0%, respectively. The existence of falsely-negative and falsely-positive results reinforces the use of complementary diagnostic procedures, such as DME and culture, for confirmatory testing.
CONCLUSIONS: In conclusion, the PreventID Dermatophyte test provides rapid and reliable results with acceptable performance.
METHODS: Between February and July 2024, 48 nail samples, collected at the Navarra University Hospital, Spain, were included in the evaluation. In addition to DME and culture, the RAD test was executed. In case of discrepancies, the qPCR assay Novaplex™ Dermatophyte was utilized.
RESULTS: Overall, the RAD test performed well, comparable to DME or culture, with concordances of 80.9% and 80.0%, respectively. The existence of falsely-negative and falsely-positive results reinforces the use of complementary diagnostic procedures, such as DME and culture, for confirmatory testing.
CONCLUSIONS: In conclusion, the PreventID Dermatophyte test provides rapid and reliable results with acceptable performance.