Transcatheter Edge-to-Edge Repair With the PASCAL Precision System: Advanced Catheter Steering Maneuvers for Mitral and Tricuspid Interventions.

Transcatheter edge-to-edge repair (TEER) has become the most common percutaneous technique for patients affected by severe regurgitation, either mitral or tricuspid, as recommended by the latest European and American guidelines on valvular heart disease. Among the available devices, the PASCAL Precision system (Edwards Lifesciences, Irvine, California) is the latest technology introduced on the market, with a CE Mark obtained in 2019 for MR and in 2020 for TR treatment. Several studies have demonstrated its safety and effectiveness in both the treatment of MR and TR, but optimal TEER results are closely connected to the operator's experience. In this perspective, the aim of the present manuscript is to provide a full guide on basic and advanced movements of the PASCAL system for the treatment of MR and TR.